Mobile DNA Group
Mobile genetic elements, generically called transposable elements (TE), are found in the genomes of nearly every organism studied to date, often accounting for a sizable fraction of the host genome (see figure). Transposon replication causes chromosomal aberrations through insertions and deletions. Most transposons are believed to be genomic parasites, although more and more examples of element domestication are being discovered. It is important from genetic, genomic, and evolutionary perspectives to understand how transposons replicate and the impact transposons have had on the evolution of the host genome and the organism as a whole.
The Mobile DNA Group studies transposon biology: the evolution, genomic impacts, and replication mechanisms of transposons. The Mobile DNA Group consists of the Pritham, Feschotte, Betrán, and Christensen labs at the University of Texas Arlington, Department of Biology. We hold regular joint lab meetings.
If you are a prospective graduate student and are interested in studying DNA transposons, retrotransposons, retrotransposed genes, and genomics, the University of Texas Arlington is an outstanding place to be. Apply to our biology Ph.D. or M.S. program and become a member of one of our esteemed labs! Not sure which lab suits you best, sign up to do lab rotations during your first semester (or two), then choose one of our labs to do your thesis work in. We look forward to hearing from you.
Mobile DNA Group
Feschotte, unpublished data
